Prevention of Oculocardiac Reflex by Premedication With Low Dose I/V Ketamine during Strabismus Surgery

Background: OCR commonly occurs during strabismus surgery, producing bradycardia, arrhythmias and even cardiac arrest after manipulation of orbital structures. Ketamine is NMDA receptor antagonist acts as an analgesic. Aim: To determine the effect ketamine premedication on prevention surgery. Study design: Randomized control trial Methodology: 60 patients were randomly divided into two groups i.e., 0.75mg/kg (Group K) C). Group K premedicated with while C did not receive any premedication. Heart rate ECG observed 30 sec before continuously traction extraocular muscles was applied upto end surgery for bradycardia arrhythmias. Percentage change in HR presence documented. All data collected using case report form analyzed SPSS version 15. Results: In C, 15(50%) cases had K, only 4(13.33%) Mean 118.77±6.92/min 101.57±15.65/min. oculocardiac reflex present 23(76.7%) 6 (20%) prevented 24 (80%) cases. Conclusion: Premedication IV significantly reduces occurrence Keywords: Ketamine, Oculocardiac Reflex, Premedication, Prevention, Strabismus